Alison Morris has an interesting handselling report at her PW blog, Shelftalker: A Children's Bookseller's Blog. Note that many of the titles her booksellers report handselling are not necessarily Big Name books. And, yet, the books are selling nonetheless.
Also pay attention to the quote from a speech by Karl Pohrt. He talks about selling the top selling 500 titles. While independent bookstores sell only 9 to 10 percent of the top 150 books, they exceed their market share for titles in the 150 to 500 range. He also says, "It should also be noted that the 150 to 500 range of titles is where publishers are making money, because they haven’t made huge investments that they have to recuperate in contracts with best-selling authors and large ad campaigns."
I've heard something similar before, but only recently. I find it extremely interesting, because years ago many in the publishing industry justified huge advances to bestselling authors by claiming those authors made big money for publishers, making it possible for them to use their profits to take risks on new writers/literary writers/you name it. That's not the case anymore?